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KMID : 0895820080180020131
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Journal of Oriental Rehabilitation Medicine
2008 Volume.18 No. 2 p.131 ~ p.142
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The Influence of Predisposing Factors and Sign of Hypoadrenia on Autonomic Nervous System Activity and Salivary Cortisol
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Lee Jung-Ho
Kim Ho-Jun
Lee Myeong-Jong
Kim Sung-Min
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Abstract
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Objectives :This study was performed to identify the influence of salivary cortisol and HRV(Heart rate variability) on hypoadrenia predisposing factors and sign.
Methods :30 patients with chronic fatigue symptom belonging to Shen xu(腎虛) were recruited for investigation from March to April 2007. The participants were divided into HS(High score) group(n=15) and LS(Low score) group(n=15) in predisposing factors of adrenal questionnaire. At the same time equal patients separated into OH(+)(Orthostatic hypotension positive) group(n=12) and OH(-)(Orthostatic hypotension negative) group(n=18). Salivary cortisol and HRV made use of evaluating hormonal imbalance and autonomic nervous system of hypoadrenia.
Results :Salivary cortisol at P.M.4 in HS group was significantly(p=0.011) lower than LS group. And LF(Low frequency) of OH(+) group was considerably(p=0.014) lower than OH(-) group.
Conclusion : Shen xu bian zheng(腎虛辨證), measure of orthostatic hypotension, predisposing factors of adrenal questionnaire, salivary cortisol and HRV deserve clinical application for management of subclinical hypoadrenia.
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KEYWORD
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Hypoadrenia, Orthostatic hypotension, HRV, Salivary cortisol
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